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Linked Patient Learning
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Most biopharma patient engagement programs optimize the 10% of the journey. The 90/10 Framework maps cross-vendor handoffs, identifies where patients go invisible, and enables proactive outreach before discontinuation happens - across the full patient ecosystem.
Biopharma has built exceptional infrastructure for activation: enrollment, benefit verification, first-fill, HCP education. These moments — the visible 10% — receive 70% of patient support investment.
But persistence is determined in the other 90%. At home. Between appointments. In the handoff gap between your hub and your specialty pharmacy. In the silence after a side effect that never got reported. In the refill that almost happened but didn't.
Standard hub and platform metrics don't capture any of it — because they were never designed to.
Typical biopharma patient engagement infrastructure allocation vs. where discontinuation actually occurs.
The 90/10 Framework is a comprehensive patient engagement program that helps biopharma patient experience leaders map the complete patient ecosystem, identify cross-vendor handoff failures, and deploy proactive outreach strategies — closing the visibility gap in the 90% of the patient journey that hub and platform metrics cannot reach.
Developed by a 22-year pharmaceutical veteran who has activated over 200,000 patients across rare disease programs, The 90/10 Framework combines strategic ecosystem mapping, proactive patient outreach design, and cross-vendor data integration into a single, cohesive program architecture.
It is not a point solution. It is not another vendor. It is the strategic layer that unifies your existing patient engagement infrastructure — and reveals what it cannot see on its own.
The framework operates across three integrated components — each designed to address a specific failure mode in conventional patient engagement programs.
Map every player in your patient ecosystem — HCPs, hubs, specialty pharmacies, copay administrators, advocacy organizations, payers, and care coordinators. Identify where patients cross vendor boundaries, where handoff accountability breaks down, and which touchpoints in the 90% are currently invisible to your program metrics.
Design and deploy outreach strategies that reach patients before they discontinue — not after. Build trigger-based communication pathways keyed to refill windows, handoff events, and at-risk signals. Move from reactive call-center support to proactive, personalized outreach across the full 90% of the care journey.
Replace siloed vendor scorecards with ecosystem-level measurement. Develop cross-vendor KPIs, unified patient journey dashboards, and business case frameworks that connect engagement investment to clinical persistence, population health outcomes, and commercial return — giving you evidence for every stakeholder conversation.
A structured engagement model that builds from diagnostic clarity to measurable infrastructure change.
A structured diagnostic that maps your current patient engagement program against the 90/10 benchmark. You'll receive a scored analysis of where your infrastructure is optimized, where handoff failures occur, and where the 90% of your patient journey goes dark.
Free 3-minute assessment availableWe map all stakeholders, vendors, and care coordination touchpoints in your patient journey — including the informal ones. Every cross-vendor handoff is documented. Every intervention point is identified. You'll see the full patient journey for the first time, including what your current program cannot see.
Based on the ecosystem map, we design proactive outreach triggers and communication pathways for the at-risk patient moments in the 90%. This includes refill risk windows, handoff failure signals, side-effect management gaps, and life-disruption events that currently go undetected and unaddressed.
Connect your existing hub, specialty pharmacy, copay, and engagement platform data into a unified patient view. Integrate AI-powered predictive analytics that flag discontinuation risk before it becomes a missed refill — so your team can intervene while there's still time to make a difference.
Build the evidence framework that connects your 90% infrastructure investment to clinical outcomes (persistence rates, days on therapy) and commercial return (cost-per-persistent-patient, revenue at risk from discontinuation). Translate patient engagement strategy into the language of your CFO, brand team, and payer partners.
The 90/10 Framework moves patient engagement programs from reactive vendor management to proactive ecosystem orchestration.
Proactive outreach at the right moments in the 90% — refill windows, handoff events, side-effect peaks — directly reduces unexplained discontinuation. When patients get support before they drop off, they stay on therapy longer.
Ecosystem mapping reveals the patient signals that your current infrastructure cannot see. You'll identify at-risk patients earlier, understand why patients who enrolled never filled, and reconstruct the handoff failures behind unexplained discontinuation.
Replace fragmented vendor scorecards with a single, integrated view of every patient's journey — across your hub, specialty pharmacy, copay administrator, and digital engagement platforms. Know the full story, not just each vendor's 10%.
Connect your patient support budget to persistence outcomes and commercial return. Build the business case framework that justifies 90% infrastructure investment to leadership — and demonstrates exactly where your program is creating and losing patient value.
The program is designed for biopharma leaders accountable for patient engagement outcomes — particularly in rare disease, specialty, and complex chronic therapy areas where persistence is commercially critical.
Building the infrastructure strategy across your patient support ecosystem and consolidating vendor performance into unified outcomes.
Accountable for what happens to patients after enrollment — and for reducing unexplained discontinuation across the full journey.
Connecting patient support investment to persistence outcomes, revenue protection, and competitive differentiation in rare disease markets.
Designing care coordination and population health management programs that go beyond access barriers to sustained patient support at scale.
The 90/10 Framework is a strategic consulting program — not a software platform you purchase and deploy. Linked Patient Learning designs the ecosystem mapping, outreach infrastructure, and measurement frameworks alongside your team, and integrates with the platforms and vendors you already have. We are the strategic layer above your existing stack, not a replacement for it.
The 90/10 Framework creates unified visibility across your existing vendor infrastructure — hub, specialty pharmacy, copay administrator, digital engagement platforms — without requiring you to replace any of them. We connect vendor data and design cross-vendor patient journey visibility so you see the full patient story, not each vendor's partial view.
The framework was developed through deep experience in rare disease and oncology, where patient persistence and ecosystem complexity are highest. It applies wherever the gap between enrollment and sustained therapy matters commercially — rare disease, specialty biologics, chronic complex conditions, and any indication where unexplained discontinuation represents meaningful revenue and patient harm.
We build measurement frameworks that connect 90% infrastructure investment to both clinical outcomes (persistence rates, days on therapy, refill rates) and commercial return (cost-per-persistent-patient, revenue protected from discontinuation). Every engagement includes a business case model that translates patient engagement strategy into the financial language of your leadership team and brand P&L.
Start with the free 90/10 Gap Assessment. In 3 minutes, you'll receive a scored analysis of your current patient engagement infrastructure — identifying specific visibility gaps, handoff failure points, and whether your program is optimized for the 10% (activation) or the 90% (sustained support). No sales pressure. Just diagnostic clarity.
Take the 3-minute assessment to identify your biggest gaps — or talk directly with our team about how the 90/10 Framework applies to your program.
No sales pitch. No commitment. Just clarity on where your 90% infrastructure stands today.